As with Rune Factory: Tides of Destiny and Rune Factory 2, Rune Factory 4 has two protagonists: a male and a female. In Rune Factory 4, however, the protagonist's gender is chosen at the beginning of the game, and the same character is used for the entire storyline. By default, the male protagonist's name is Lest, and the female protagonist's name is Frey.
There have been many improvements to the game system such as the addition of pajamas for bachelors and bachelorettes, slumber parties, a new request system, and much more. The plot has also been divided into three arcs, with the first and second arcs being the main plot, and the third arc adding bonus plot and an additional dungeon.
Marvelous AQL has announced that Rune Factory 4 will not be released in Europe in the forseeable future, stating that, "While MarvelousAQL has made every effort to secure the title's release for this territory, it is, unfortunately, not possible to do so at this time."
- Rune Factory 4 is the first numbered entry (so far) to not have "A Fantasy Harvest Moon" labeled under it.
- Rune Factory 4 is the first Rune Factory game in which the player is able to choose the gender of the main character at the start of the game.
- Cooking and Recipes
- Dating and Marriage Requirements
- Ingredient Effects
- Magic and Rune Abilities
- Prince/Princess Point Rewards
- Random Events
- Shipping List
- Status ailments
- Tips From Players
- Upgrading Armor/Weapons
- World Map